Symbol | Function description |
---|---|
NOS3 | Produces nitric oxide which is implicated in vascular smooth muscle relaxation. |
CYP2E1 | An effective producer of reactive oxygen species. |
KNG1 | Precursor of vasoactive kinins. |
NPY | A peptide with direct and potential effects on vasoconstriction. |
HIF1A | Functions as a master transcriptional regulator of the adaptive response to hypoxia. |
POMC | Controls energy homeostasis. |
REN | Generates angiotensin I from angiotensinogen in the plasma. |
TNF | A proinflammatory cytokine which induce endothelial dysfunction. |
PTH | Elevates calcium level by dissolving the salts in bone and preventing their renal excretion. |
SRC | Involves in cell maintenance and communication. |
AKT1 | Phosphorylates NOS3. |
PTGER3 | Receptor for prostaglandin E2. |
INS | Decreases blood glucose concentration. |