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Table 6 The list of proteins only with high BC and their functions

From: Construction and analysis of the protein-protein interaction network related to essential hypertension

Symbol

Function description

CAT

Protects cells from the toxic effects of hydrogen peroxide.

COMT

Inactivates catecholamine neurotransmitters and catechol hormones.

CALM1

Activates NO synthesis in NOS3.

TGFB1

Controls proliferation, differentiation and other functions in many cell types.

CACNA2D1

Calcium channel, voltage-dependent, alpha 2/delta subunit 1.

SIRT1

NAD-dependent protein deacetylase.

IFNG

Has an important immunoregulatory function.

RGS5

A potent GTPase-activating protein for Giα and Gqα.

GRK4

Specifically phosphorylates the activated forms of G protein-coupled receptors.

TRPV5

Actives calcium selective cation channel involved in Ca (2+) reabsorption.

ATP1B1

Maintains the normal gradients of Na (+) and K (+) across plasma membrane.

SELE

Cell-surface glycoprotein having a role in immunoadhesion.

GNAQ

Acts as an activator of phospholipase C.

SP1

Activates or represses transcription in response to stimuli.