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Figure 6 | BMC Systems Biology

Figure 6

From: Stat and interferon genes identified by network analysis differentially regulate primitive and definitive erythropoiesis

Figure 6

IFNγ differentially modulates definitive erythroid colony formation. Erythroid progenitor assays were performed on single-cell suspensions of dissociated murine E8.5 embryos (EryP-CFC) and adult bone marrow (CFU-E) in the presence or absence of IFNγ (10 ng/ml). CFU-E and EryP-CFC colonies were identified by morphologic criteria and scored at 2–3 and 5 days, respectively. Values for IFN-treated cultures are presented as normalized to vehicle-treated (phosphate buffer) control cultures.

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