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Table 4 Parameter values used to replicate cAMP dynamics for the phosphodiesterase mutants, pde1 Δ and pde2 Δ in the Σ 1278b background

From: Modeling mutant phenotypes and oscillatory dynamics in the Saccharomyces cerevisiae cAMP-PKA pathway

Parameter

wt

p d e 1Δ

p d e 2Δ

M

0.085

0.262

0.121

D

0.247

0.0112

0.107

Γ

0.32

0.04

0.061

  1. For all three cases, the time scale parameter T =0.17.