Figure 4From: Computational modelling of the regulation of Insulin signalling by oxidative stressEffects of external oxidative stress “preconditioning” on later effect of higher oxidative stress. (A): Insulin = 0; effect of various initial external ROS for 1440 min, followed by moderate external ROS of 20 μM for 20000 min, on Total FOXO, DNA bound FOXO, SOD2, cytoplasmic ROS and total IRS; (B): as before, but with Insulin = 0.2 nM (# = 1000).Back to article page