Figure 6

Distributions of four dynamic patterns of the individual time-series curves of nuclear NF-кB profiles for an ensemble of 1,000 replicates of the wild type, A20 knocked-out mutant, and three IкB genes double knocked-out mutants. A few examples of four dynamic patterns are plotted in the top panel: (A) single-peaked pattern (blue), (B) under-damped oscillation (red), (C) hyperbolic pattern (black), and (D) sustained oscillation (yellow) where color within a parenthesis denotes color in the bottom panel. Individual time-series curves are classified as one of the four dynamic patterns.