Table 1 Metabolic model information and reaction subsystem classification

Genomes included in analysis

1

23

39

72

Genes

1339

790

683

325

Reactions Total

2,128

1,674

1,601

1,191

Orphan Reactions

100

207

272

677

Reactions by subsystem

Alternate Carbon Metabolism

192

73

64

37

Amino Acid Metabolism

170

144

139

121

Anaplerotic Reactions

8

6

6

4

Carnitine Degradation

1

0

0

0

Cell Envelope Biosynthesis

134

118

118

104

Citric Acid Cycle

13

10

10

9

Cofactor and Prosthetic Group Biosynthesis

164

148

147

131

Folate Metabolism

6

6

5

4

Glycerophospholipid Metabolism

225

191

191

75

Glycine Betaine Biosynthesis

1

1

1

1

Glycolysis/Gluconeogenesis

22

20

19

15

Glyoxylate Metabolism

4

2

2

2

Inorganic Ion Transport and Metabolism

105

97

91

63

Lipopolysaccharide Biosynthesis / Recycling

68

52

49

46

Membrane Lipid Metabolism

46

34

33

15

Methylglyoxal Metabolism

8

7

7

5

Murein Biosynthesis

15

15

15

15

Murein Recycling

38

34

31

17

Nitrogen Metabolism

13

4

3

0

Nucleotide Salvage Pathway

131

101

92

77

Oxidative Phosphorylation

55

39

36

10

Pentose Phosphate Pathway

10

9

9

6

Purine and Pyrimidine Biosynthesis

26

24

24

22

Pyruvate Metabolism

10

8

7

6

Transport, Inner Membrane

307

198

174

103

Transport, Outer Membrane

39

28

25

9

Transport, Outer Membrane Porin

247

247

247

247

tRNA Charging

22

18

18

14

Unassigned

37

28

26

21