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Table 2 Excerpt of the C 2 Card centered at the reaction ‘l-arginine + H 2 O → ornithine + urea’

From: Consensus and conflict cards for metabolic pathway databases

Database

Reaction

Overlap (%)

EC number

Gene

Pathway

H. sapiens Recon 1

l-arginine[c] + H2O[c]

→

100

3.5.3.1

ARG1

Urea cycle / amino group metabolism

 

ornithine[c] + urea[c]

    
 

l-arginine[m] + H2O[m]

→

100

3.5.3.1

ARG2

Urea cycle / amino group metabolism

 

ornithine[m] + urea[m]

    

Reactome

l-arginine[c] + H2O[c]

→

66

3.5.3.1

ARG1

Urea Cycle

 

l-ornithine[c] + urea[c]

    
 

l-arginine[m] + H2O[m]

→

66

3.5.3.1

ARG2

Urea Cycle

 

l-ornithine[m] + urea[m]

    
  1. One metabolite was allowed not to match in this reaction search. The only difference between the reactions is the use of ornithine versus l-ornithine (both in bold). Note that H2O is not taken into account for computing the percentage of overlap. ‘[c]’ stands for cytosol and ‘[m]’ for mitochondrion.