Figure 9

Examples of potential transcriptional networks. (A) A top-tier/’broad’-domain regulator (FGSG_12970) is shown with its putative binding site (sequence logo) in the promoters of genes comprising the FG6↓ co-expression group together with its similarity to the S. cerevisiae RIM101/PacC DNA-binding site. An arrow indicates possible interactions between the regulator and target promoters, with circles indicating second-tier regulators and their fill colours representing DBDs as described in Figure 8A. One second-tier regulator, aurR1, regulates the TC1 biosynthetic cluster (indicated by dotted line). (B) The sequence logo for a ‘narrow’-domain regulator (FGSG_08010) is displayed with its homologous UME6 binding site in budding yeast and putative target genes in the FG2.10 co-expression group and lying in the LC12 cluster.