Figure 4From: The systems biology simulation core algorithmRefined step-size adaptation for events. For a certain time interval, the Rosenbrock solver (KiSAO term 33) always tries to increase time t by the current adaptive step size h and calculates a new vector of quantities Q → next . After a successful step, the events and rules of the model are processed. If this causes a change in Q → , h is first decreased and the Rosenbrock solver then calculates another vector Q → next using this adapted step size. The precision of the event processing is therefore determined by the minimum step size hmin. The adapt function is defined by Rosenbrock’s method[30].Back to article page