Skip to main content

Table 2 Apoptotic gate types resulting from considered Bcl-2 family protein levels

From: Levels of pro-apoptotic regulator Bad and anti-apoptotic regulator Bcl-xL determine the type of the apoptotic logic gate

Protein levels

Gate type

Bax tot

Bcl-x L tot

Bad tot

 

dynamic

1 × 10 5

2 × 10 5

OR

dynamic

1 × 10 5

0.6 × 10 5

AND

dynamic

2.4 × 10 5

2 × 10 5

AND*

  1. Levels of total Bcl-xL and Bad are assumed constant while the level of total Bax is dynamically regulated.
Back to article page

BMC Systems Biology

ISSN: 1752-0509

Contact us