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Table 5 Algebraic conditions for outputs of the AND and AND* gates

From: Levels of pro-apoptotic regulator Bad and anti-apoptotic regulator Bcl-xL determine the type of the apoptotic logic gate

Gates AND and AND*

Inputs

Output

Condition for the output

{0,0}

Survival

m1+(1−m6)Badtot<Bcl-x L +m7

{1,0}

Survival

m2+(1−m6)Badtot>Bcl-x L +m7

{0,1}

Survival

m1+Badtot>Bcl-x L +m7

{1,1}

Apoptosis

m2+Badtot>Bcl-x L +m7

  1. Input in the format {i,j} denotes p 53killer =i × 2 × 105,Aktu =j × 2 × 105. It is assumed thatm3 ≪m4.