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Figure 4 | BMC Systems Biology

Figure 4

From: Reconstruction of large-scale regulatory networks based on perturbation graphs and transitive reduction: improved methods and their evaluation

Figure 4

Performance and robustness of the perturbation graph methodology PGnew applied to the 9 noise configurations of network 1 in the SysGenSIM dataset. The AUPR scores of PGnew are fairly robust for a large range of meaningful parameter values β and γ. The picture shows the performance of the inference of Network 1 (containing about 7500 edges) with respect to the 9 different noise conditions. Similar behaviors can be seen for the other networks (see Figures F1 and F2 in Additional file 1).

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