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Figure 4 | BMC Systems Biology

Figure 4

From: New network topology approaches reveal differential correlation patterns in breast cancer

Figure 4

Correlation networks of genes with higher correlation in ER- tumors compared to ER+ tumors. (A) Algorithm DCglob, p<0.05: Correlation networks in ER- breast cancer (left panel) and ER+ breast cancer (right panel). In this case, almost all the subnetworks present in ER- breast cancer are disorganized in ER+ breast cancer. Genes are connected by an edge if their Pearson correlation is larger than 0.5. The size of nodes in both networks is proportional to the degree of nodes in the network of ER- breast cancer. (B) Algorithm DCloc, d>0.3: Correlation networks in ER- breast cancer (left panel) and ER+ breast cancer (right panel).

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