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Table 3 Identified final modules between blood and brain regions with the associated mean AUC and mean error rate of both tissues

From: Core modular blood and brain biomarkers in social defeat mouse model for post traumatic stress disorder

Validation

HB

AY

HC

ST

MPFC

SE

VS

Core module

Core gene

Inference

Blood

92

20

23

27

22

2

19

9

43

Final gene

171

52

51

70

72

7

44

 

Mean AUC

0.73

0.85

0.79

0.86

0.76

0.82

0.84

Mean error rate

0.24

0.24

0.29

0.22

0.31

0.27

0.24

  1. The mean AUC and error rate were calculated by 500 LDA classifiers with random sampling on both tissues. (HB hemibrain (hemisphere), AY amygdala, HS hippocampus, MPFC medial prefrontal cortex, VS ventral striatum, SE septal region and ST stria terminalis).
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BMC Systems Biology

ISSN: 1752-0509

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