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Table 3 Reactions predicted by iRsp1095 to be involved in NADPH generation

From: Global insights into energetic and metabolic networks in Rhodobacter sphaeroides

Gene identifier Enzyme name Reaction catalyzed* EC number
RSP_0239 & RSP_0240 PntAB NADP+ + NADH + 2 H+[p] = > NADPH + NAD+ + 2 H+ 1.6.1.2
RSP_1939 NADPH-ferredoxin reductase Reduced ferredoxin + NADP+ + H + <= > Oxidized ferredoxin + NADPH 1.18.1.2
RSP_2734 Zwf D-Glucose 6-phosphate + NADP+ < = > 6PGL + NADPH 1.1.1.49
RSP_1217 Malic enzyme (S)-Malate + NADP+ = > Pyruvate + CO2 + NADPH 1.1.1.40
RSP_1593    
RSP_0661 THF dehydrogenase mlthf + NADP+ < = > methf + NADPH 1.5.1.5
RSP_0446 Icd Isocitrate + NADP+ < = > 2-Oxoglutarate + CO2 + NADPH 1.1.1.42
RSP_1559    
RSP_1146 & RSP_1149 Glutamate synthase 2 L-Glutamate + NADP+ < = > L-Glutamine + 2-Oxoglutarate + NADPH + H+ 1.4.1.13
  1. *6PGL – D-Glucono-1,5-lactone 6-phosphate; mlthf – 5,10-Methylenetetrahydrofolate; methf – 5,10-Methenyltetrahydrofolate; THF dehydrogenase – 5,10-methylene-tetrahydrofolate dehydrogenase.