Figure 2From: Analysis of l-glutamic acid fermentation by using a dynamic metabolic simulation model of Escherichia coliPredicted mechanism underlying changes in l -glutamic acid production by pgk gene amplification. A schematic representation of the simplified metabolic pathway from GA3P to l-glutamic acid. The effect of increased 3-phosphoglycerate concentration on phosphorylation of isocitrate dehydrogenase is indicated.Back to article page