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Table 2 Over-representation analysis for the genes significantly associated after integration with genes that are differentially regulated during LPS stimulation

From: JunD/AP1 regulatory network analysis during macrophage activation in a rat model of crescentic glomerulonephritis

   WKY WKYL.Crgn2
Control v 2 hrs Control v 4 hrs Control v 8 hrs Control v 2 hrs Control v 4 hrs Control v 8 hrs
Transfac matrix ID TF Upregulated TF-targets P-value Upregulated TF-targets P-value Upregulated TF-targets P-value Upregulated TF-targets P-value Upregulated TF-targets P-value Upregulated TF-targets P-value
GATA2_01 GATA2 39 NS 153 3.38e-07 105 0.04 36 NS 102 NS 96 NS
GATA2 GATA2 39 NS 153 3.38e-07 105 0.04 36 NS 102 NS 96 NS
MYOD_Q6 MYOD 31 NS 90 1.94e-06 63 0.01 28 NS 66 0.009 59 0.03
MAF MAF 51 NS 168 5.62e-06 114 NS 44 NS 105 NS 106 NS
T3R T3R 47 NS 178 5.82e-06 127 0.05 44 NS 121 NS 120 NS
E2A_Q6 E2A 33 NS 96 7.29e-06 69 0.01 32 NS 69 0.03 61 NS
AP1_Q6_01 AP1 30 NS 118 3.86e-05 89 0.01 28 NS 80 NS 82 0.042
CEBPA_01 CEBPA 19 NS 93 5.35e-05 60 NS 22 NS 61 NS 56 NS
AP3_Q6 AP3 40 NS 146 7.09e-05 101 NS 35 NS 99 NS 94 NS
CREB_Q3 CREB 31 NS 120 0.0001 89 0.03 31 NS 80 NS 82 NS
  1. Top-ten most significantly enriched interacting TF at 4 hrs WKY time-point is listed here, for complete list please refer to Additional file 8: Table S8. NS, P > 0.05.