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Table 2 Over-representation analysis for the genes significantly associated after integration with genes that are differentially regulated during LPS stimulation

From: JunD/AP1 regulatory network analysis during macrophage activation in a rat model of crescentic glomerulonephritis

  

WKY

WKYL.Crgn2

Control v 2 hrs

Control v 4 hrs

Control v 8 hrs

Control v 2 hrs

Control v 4 hrs

Control v 8 hrs

Transfac matrix ID

TF

Upregulated TF-targets

P-value

Upregulated TF-targets

P-value

Upregulated TF-targets

P-value

Upregulated TF-targets

P-value

Upregulated TF-targets

P-value

Upregulated TF-targets

P-value

GATA2_01

GATA2

39

NS

153

3.38e-07

105

0.04

36

NS

102

NS

96

NS

GATA2

GATA2

39

NS

153

3.38e-07

105

0.04

36

NS

102

NS

96

NS

MYOD_Q6

MYOD

31

NS

90

1.94e-06

63

0.01

28

NS

66

0.009

59

0.03

MAF

MAF

51

NS

168

5.62e-06

114

NS

44

NS

105

NS

106

NS

T3R

T3R

47

NS

178

5.82e-06

127

0.05

44

NS

121

NS

120

NS

E2A_Q6

E2A

33

NS

96

7.29e-06

69

0.01

32

NS

69

0.03

61

NS

AP1_Q6_01

AP1

30

NS

118

3.86e-05

89

0.01

28

NS

80

NS

82

0.042

CEBPA_01

CEBPA

19

NS

93

5.35e-05

60

NS

22

NS

61

NS

56

NS

AP3_Q6

AP3

40

NS

146

7.09e-05

101

NS

35

NS

99

NS

94

NS

CREB_Q3

CREB

31

NS

120

0.0001

89

0.03

31

NS

80

NS

82

NS

  1. Top-ten most significantly enriched interacting TF at 4 hrs WKY time-point is listed here, for complete list please refer to Additional file 8: Table S8. NS, P > 0.05.