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Figure 6 | BMC Systems Biology

Figure 6

From: The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models

Figure 6

The T reg kinetic model incorporated in FIRM. The model accounts for Treg presence in the lymphoid T (where they differentiate from naïve T-cells), the blood (where they migrate and are subject to removal or recruitment to the target organ) and the target organ (where they proliferate). The kinetics of TGF-β are similarly accounted for. Treg, regulatory T-cells; TGF-β, tumor growth factor beta; other abbreviations as in Figure 1A and Figure 1B. See text for details.

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BMC Systems Biology

ISSN: 1752-0509

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