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Table 1 Conserved residues among carbamoyltransferases

From: Identifying reaction modules in metabolic pathways: bioinformatic deduction and experimental validation of a new putative route in purine catabolism

Enzyme family Common TCase motifs ATCase motif
  (Positions in Escherichia coli ATCase)
  1 2 3 4
  S53-T56 H135-Q138 H265-P268 R230-Q232
OTCase S[LT]RT HPXQ HCLP --
AOTCase, SOTCase S[LM]RT HP[LC]Q HCLP --
YTCase S[LT]RT HP[TMF]Q H[AVC]LP --
abTCase STRT HPTQ HDLP --
ATCase (I & II) S[TR]RT HP[ST]Q HP[LG]P RXQ
pseudo-ATCase 1 STRT HPTQ HPLA AIA or AIS or SIA
pseudo-ATCase 2 STRT HPTQ H[ST]LP GX[SC]
pseudo-ATCase 3 STRT HPTQ HSLP VXP
  1. The structural motifs specific for each subgroup of pseudo-ATCases are in bold.