Identifying reaction modules in metabolic pathways: bioinformatic deduction and experimental validation of a new putative route in purine catabolism

Table 2 Genomic context of the Rubrobacter xylanophilus pseudo-ATCase

Gene id	Uniprot AC	Uniprot annotation	Proposed annotation
Rxyl_2840	Q1AS76	uracil/xanthine permease	uracil/xanthine permease
Rxyl_2841	Q1AS75	uncharacterized protein	OHCU decarboxylase
Rxyl_2842	Q1AS74	CMP/dCMP deaminase,	CMP/dCMP deaminase
Rxyl_2843	Q1AS73	uricase	uricase
Rxyl_2844	Q1AS72	5-hydroxyisourate hydrolase	5HIU hydrolase
Rxyl_2845	Q1AS71	allantoinase	allantoinase
Rxyl_2846	Q1AS70	uncharacterized protein	Unknown
Rxyl_2847	Q1AS69	ATCase	see text
Rxyl_2848	Q1AS68	carbamate kinase	carbamate kinase
Rxyl_2849	Q1AS67	asparaginase	see text
Rxyl_2850	Q1AS66	transcriptional regulator	transcriptional regulator

UniprotKB data are as published in UniProt release 2013_05 (May 1, 2013). The annotations proposed for genes Rxyl_2847 and Rxyl_2849 are detailed in the text (see text in bold).

ISSN: 1752-0509