Table 3 Pathway enrichment analysis of NMR-missing genes*
From: Investigation of anti-cancer mechanisms by comparative analysis of naked mole rat and rat
pathway ID | pathway name | gene number | total number | p-value |
|---|---|---|---|---|
rno04740 | Olfactory transduction | 518 | 1015 | 1.4E-11 |
rno03010 | Ribosome | 18 | 91 | 4.4E-07 |
rno04060 | Cytokine-cytokine receptor interaction | 31 | 247 | 2.0E-06 |
rno04080 | Neuroactive ligand-receptor interaction | 31 | 290 | 5.1E-05 |
rno00190 | Oxidative phosphorylation | 26 | 244 | 2.1E-04 |
rno04115 | p53 signaling pathway | 12 | 80 | 5.6E-04 |
rno05200 | Pathways in cancer | 29 | 317 | 1.2E-03 |
rno04330 | Notch signaling pathway | 8 | 47 | 2.0E-03 |
rno05014 | Amyotrophic lateral sclerosis | 10 | 69 | 2.0E-03 |
rno04610 | Complement and coagulation cascades | 10 | 69 | 2.0E-03 |
rno05219 | Bladder cancer | 7 | 38 | 2.4E-03 |
rno04310 | Wnt signaling pathway | 16 | 149 | 3.0E-03 |
rno04650 | Natural killer cell mediated cytotoxicity | 14 | 125 | 3.6E-03 |
rno03050 | Proteasome | 8 | 52 | 3.8E-03 |
rno04210 | Apoptosis | 12 | 107 | 6.8E-03 |
rno04010 | MAPK signaling pathway | 19 | 213 | 9.9E-03 |