Illustration of biological theme enrichment. DE-miRNAs shared by at least three datasets were extracted to identify target genes; these genes were then mapped to databases to identify enriched GO terms (FDR < 0.001), KEGG pathways (p < 0.001), and GeneGO pathways (FDR < 0.001). Top GO terms, KEGG, and GeneGO pathways are shown. Terms shown in the box to the right of each bar plot are the most significant ones. Details are available in Additional files 3, 4, 5.