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Table 2 Description of the selected gene features between short-term and long-term survival group in GBM

From: Intra-relation reconstruction from inter-relation: miRNA to gene expression

Gene

Region

Function

Up/down

AUC_diff

RAGE

14q32.31

Renal tumor antigen/threonine kinase activity/transferase activity

Up

0.028

ATAD3A

1p36.33

ATP binding/nucleotide binding

Down

0.024

HEMK1

3p21.31

DNA binding/N-methyltransferase activity

Up

0.012

KMO

1q43

Integral to membrane/kynurenine 3-monooxygenase activity

Up

0.012

RBKS

2p23.2

D-ribose metabolic process/ribokinase activity

Up

0.012

CCNJL

5q33.3

Nucleus/regulation of progression through cell cycle

Down

0.008

LGALS8

1q43

Extracellular space/sugar binding

Up

0.008

UPP1

7p12.3

Cytoplasm/nucleoside metabolic process/nucleotide catabolic process

Up

0.008

BDH1

3q29

3-hydroxybutyrate dehydrogenase activity/metabolic process/mitochondrial inner membrane/mitochondrial matrix

Up

0.004

HFE

6p22.1

Antigen processing and presentation/ immune response/ protein complex assembly

Up

0.004

TUSC2

3p21.31

Cell cycle/cell proliferation/cell-cell signalling/negative regulation of progression through cell cycle

Up

0.000

  1. The gene lists in the first column were sorted by the AUC_diff, which calculated the difference between the original AUC with 11 gene features and the AUC without one gene among 11 gene features.