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Table 2 Selected top E. coli five gene pairs predicated using literature data before 2004 and verified by literature data afterwards.

From: A genome-wide MeSH-based literature mining system predicts implicit gene-to-gene relationships and networks

Index Gene1 Gene2 Dissim Score p-value PMIDs MeSH terms
1 bacA ybjG 0.073 3.83E-05 15778224, 17660416, 18411271 Polyisoprenyl Phosphates || Bacitracin || Phosphoric Monoester Hydrolases || Fosfomycin || Periplasm
2 nuoA nuoN 0.075 4.25E-05 15683249, 16645316, 16807239, 17489563 Electron Transport Complex I || NADH Dehydrogenase || Iron-Sulfur Proteins || NADH, NADPH Oxidoreductases || Electron Spin Resonance Spectroscopy
3 ybjG lpxT 0.098 5.84E-05 15778224, 17660416, 18411271 Polyisoprenyl Phosphates || Bacitracin || Fosfomycin || Phosphoric Monoester Hydrolases || Periplasm
4 hyaB hybC 0.110 7.53E-05 17668201, 17938909, 18335216 Hydrogenase || Hydrogen || Genetic Enhancement || Formate Dehydrogenases || Paraquat
5 dsdC sdaA 0.144 1.18E-04 17785472 L-Serine Dehydratase || Serine || Amino Acid Transport Systems || Urinary Tract || Transcription Factors