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Table 1 The 2x2 table used to calculate the chi-squared statistic.

From: Weighted set enrichment of gene expression data

  Genes on Array Significant Genes  
In Pathway n11 n12 N1r = n11 + n12
Not in Pathway n21 n22 N2r = n21 + n22
  N1c = n11+n21 N2c = n12+n22 N = n11+n12+n21+n22