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Table 4 Comparison of the functional enrichment of protein complexes identified by LF-PIN and other algorithms (for S.cerevisia e)

From: Identifying protein complexes based on density and modularity in protein-protein interaction network

Algorithms <E-10 [E-10,E-5] [E-5, 0.01] ≥0.01 insignificant <0.01 significant
LF-PIN 63(21.2%) 93(31.3%) 103(34.7%) 38(12.8%) 259(87.2%)
CMC 73(6.5%) 191(16.9%) 292(25.9%) 574(50.8%) 556(49.2%)
Core-Attachment 76(5.6%) 122(9.0%) 287(21.1%) 873(64.3%) 485(35.7%)
CPM 25(12.7%) 49(24.9%) 42(21.3%) 81(41.1%) 116(58.9%)
DPClus 42(3.5%) 155(12.9%) 329(27.4%) 674(56.2%) 526(43.8%)
HC-PIN 40(15.1%) 42(15.9%) 84(31.7%) 99(37.4%) 166(62.6%)
MCL 54(5.8%) 114(12.3%) 239(25.7%) 522(56.2%) 407(43.8%)
NFC 63(21.2%) 81(15.6%) 124(23.9%) 266(51.3%) 259(87.2%)
  1. The table lists the percentages of protein complexes identified by LF-PIN, CMC, Core-Attachment, CPM, DPClus, HC-PIN, MCL and NFC in PPI network of S.cerevisiae whose P-value falls within < E-10, [E-10, E-5], [E-5, 0.01] and ≥0.01.