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Table 2 Topics found for GAD genetic diseases gene set

From: GeneTopics - interpretation of gene sets via literature-driven topic models

GAD gene set LDA model # Relevant number of topics Best Topic
esophageal cancer 20 7 genotyp,polymorph,risk,associ,cancer,95,gstm1,gene,or,ci,control,studi,allel,gstt1,p,patient,genet,gstp1,frequenc,signific
kidney cancer 15 2 polymorph,xrcc1,risk,repair,cancer,genotyp,dna,95,associ,ci,gene,allel,variant,control,patient,suscept,breast,frequenc,case,ratio
Alzheimer's disease 15 10 polymorph,genotyp,associ,allel,risk,gene,patient,p,popul,genet,95,variant,diseas,haplotyp,diabet,subject,frequenc,ci,snps,control
blood pressure, arterial 20 11 polymorph,genotyp,gene,associ,allel,p,risk,variant,hypertens,patient,genet,subject,popul,95,haplotyp,frequenc,ci,variat,studi,pressur
carotid atherosclerosis 10 6 eno,endotheli,ace,oxid,rat,inhibitor,nitric,group,renal,p,inhibit,day,treatment,synthas,after,vascular,arteri,heart,angiotensin,enzym
hypertension 20 14 arteri,rat,angiotensin,pressur,vascular,hypertens,heart,cardiac,receptor,renal,blood,ang,increas,ace,endotheli,ventricular,express,after,at1,muscl
cirrhosis 10 5 iron,transferrin,receptor,tfr,hfe,ferritin,cell,stfr,method,uptak,serum,assay,status,sampl,antibodi,marrow,recycl,blood,concentr,defici
hepatitis c, chronic 10 7 polymorph,il12b,genotyp,associ,allel,risk,gene,frequenc,patient,haplotyp,genet,diseas,suscept,p,popul,asthma,ci,il12,variant,95
longevity 15 7 polymorph,genotyp,gstm1,gene,risk,associ,gstt1,cancer,allel,frequenc,genet,95,null,ci,patient,control,variant,popul,individu,p
diabetes, type 2 20 14 polymorph,associ,genotyp,gene,allel,p,risk,diabet,variant,patient,subject,genet,popul,snps,type,frequenc,haplotyp,95,2,studi
  1. This table shows the best topic found by GeneTopics for gene sets derived from GAD (Genetic Association Database). Many of the best topics found are related to the common origins of the GAD gene sets.