Table 3 GeneTopics results for GAD gene sets with GAD genes as background
From: GeneTopics - interpretation of gene sets via literature-driven topic models
GAD gene set | LDA model # | Relevant number of topics | Best Topic |
|---|---|---|---|
esophageal cancer | 20 | 7 | polymorphism, genotype, risk, associated, 95, cancer, or, gene, ci, allelic, studies, gstm1, patients, controls, p, gstt1, frequency, genetic, population, variants |
kidney cancer | 15 | 2 | cyclin, d1, expressed, cancer, tumor, cells, carcinomas, breast, cases, cycle, correlated, survival, invasive, cdk4, patients, gastric, proteins, oncogene, overexpression, associated |
Alzheimer's disease | 15 | 10 | diseases, alzheimers, ad, amyloid, abeta, app, tau, brain, ide, platelets, gammasecretase, parkinsons, ps1, pd, protein, fe65, precursor, lrrk2, titin, beta |
blood pressure, arterial | 20 | 11 | renal, hypertension, ace, kidney, pressure, aldosterone, angiotensin, uroguanylin, ace2, blood, cyp11b2, sodium, enzyme, intestinal, excretion, urinary, guanylin, ae1, kae1, peptides |
hepatitis c, chronic | 10 | 7 | chemokin,cell,t,ccr5,express,rant,mcp1,cytokin,macrophag,il10,il8,cxcr1,monocyt,receptor,infect,immun,hiv1,virus,secret,neutrophil |
longevity | 15 | 7 | patients, il6, diseases, ad, clinical, therapy, serum, level, p, values, group, outcome, survival, healthy, cytokines, predicted, prognostic, stages, correlate, transplantation |
diabetes, type 2 | 20 | 14 | insulin, glucose, diabetes, leptin, adipose, muscle, obese, expression, metabolism, adiponectin, fat, fatty, mice, islets, increase, mrna, tissues, adipocytes, skeletal, levels |