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Table 4 Topics found by GeneTopics for Human islet gene expression data

From: GeneTopics - interpretation of gene sets via literature-driven topic models

Topic

Topic words

pvalue

Topic 19

endothelial, cell, vascular, expressions, activation, cytokine, receptor, il6, inhibitor, vegf, il1, growth, factor, inflammatory, matrix, angiogenesis, metalloproteinases, macrophage, inhibit, lung

9.32E-12

Topic 5

polymorphisms, associated, genes, allele, genotypes, variants, risk, p, genetic, diabetes, snps, patient, haplotype, population, subjected, frequency, variation, susceptibility, 95, snp

4.18E-08

Topic 8

rat, effects, increases, receptor, renal, after, groups, h, antagonists, day, 1, p, heart, mice, cardiac, mrna, kidney, injection, treatment, activation

4.96E-08

Topic 18

patient, p, groups, serum, levels, plasma, clinical, concentration, measured, correlation, disease, treatment, aged, n, sample, healthy, years, women, blood, vs

2.24E-07

Topic 9

insulin, glucose, pancreatic, diabetes, islet, liver, secretion, mice, acid, metabolism, obesity, fatty, betacells, ghrelin, rat, hepatitis, increases, lpa, lipid, fat

7.89E-06

Topic 6

cancer, tumor, expressions, cell, carcinoma, breast, genes, gastric, prostate, invasion, tissues, line, mrna, patient, lung, tumour, colorectal, malignant, normal, human

0.000149

Topic 20

expressions, growth, mrna, cell, collagen, activin, cartilage, matrix, factor, cultured, tissues, day, skin, igf, keratinocytes, tgfbeta, human, chondrocyte, differentially, fibroblasts

0.000153

Topic 14

binding, structure, domain, residues, enzymes, activation, site, complex, peptide, acid, substrate, protein, affinity, sequences, crystallization, form, amino, interaction, purified, nterminal

0.000228

Topic 1

added, oxidase, pedf, alzheimers, tau, apod, 5ht, nox4, polyamines, tph2, disease, ros, apolipoprotein, 5ht1b, brain, apo, d, nadph, serotonin, app

0.003461

Topic 3

developed, expressions, cell, mice, axon, embryonic, genes, differentially, embryos, signaling, neural, mutants, regulated, transcription, mouse, migrating, neurons, pattern, prox1, factor

0.00916

Topic 16

cell, t, immune, infection, receptor, expressions, mice, nk, antibody, antigen, virus, b, lymphocytes, cd8, cytokine, response, tcells, cd4, macrophage, human

0.042753