From: GeneTopics - interpretation of gene sets via literature-driven topic models
Topic | Topic words | pvalue |
---|---|---|
Topic 19 | endothelial, cell, vascular, expressions, activation, cytokine, receptor, il6, inhibitor, vegf, il1, growth, factor, inflammatory, matrix, angiogenesis, metalloproteinases, macrophage, inhibit, lung | 9.32E-12 |
Topic 5 | polymorphisms, associated, genes, allele, genotypes, variants, risk, p, genetic, diabetes, snps, patient, haplotype, population, subjected, frequency, variation, susceptibility, 95, snp | 4.18E-08 |
Topic 8 | rat, effects, increases, receptor, renal, after, groups, h, antagonists, day, 1, p, heart, mice, cardiac, mrna, kidney, injection, treatment, activation | 4.96E-08 |
Topic 18 | patient, p, groups, serum, levels, plasma, clinical, concentration, measured, correlation, disease, treatment, aged, n, sample, healthy, years, women, blood, vs | 2.24E-07 |
Topic 9 | insulin, glucose, pancreatic, diabetes, islet, liver, secretion, mice, acid, metabolism, obesity, fatty, betacells, ghrelin, rat, hepatitis, increases, lpa, lipid, fat | 7.89E-06 |
Topic 6 | cancer, tumor, expressions, cell, carcinoma, breast, genes, gastric, prostate, invasion, tissues, line, mrna, patient, lung, tumour, colorectal, malignant, normal, human | 0.000149 |
Topic 20 | expressions, growth, mrna, cell, collagen, activin, cartilage, matrix, factor, cultured, tissues, day, skin, igf, keratinocytes, tgfbeta, human, chondrocyte, differentially, fibroblasts | 0.000153 |
Topic 14 | binding, structure, domain, residues, enzymes, activation, site, complex, peptide, acid, substrate, protein, affinity, sequences, crystallization, form, amino, interaction, purified, nterminal | 0.000228 |
Topic 1 | added, oxidase, pedf, alzheimers, tau, apod, 5ht, nox4, polyamines, tph2, disease, ros, apolipoprotein, 5ht1b, brain, apo, d, nadph, serotonin, app | 0.003461 |
Topic 3 | developed, expressions, cell, mice, axon, embryonic, genes, differentially, embryos, signaling, neural, mutants, regulated, transcription, mouse, migrating, neurons, pattern, prox1, factor | 0.00916 |
Topic 16 | cell, t, immune, infection, receptor, expressions, mice, nk, antibody, antigen, virus, b, lymphocytes, cd8, cytokine, response, tcells, cd4, macrophage, human | 0.042753 |