Top levela | Gene set | HCC transitionb |
---|
 |  | N-C | C-D | D-E | E-A |
---|
0.1% | DEG | 0/11 | 1/11 | 0/11 | 1/11 |
 | DCG | 7/63* | 9/65*** | 10/60*** | 4/63 |
0.5% | DEG | 3/55 | 2/55 | 2/55 | 4/55 |
 | DCG | 25/290*** | 36/279*** | 27/287*** | 27/288*** |
1.0% | DEG | 6/110 | 3/110 | 5/110 | 6/110 |
 | DCG | 47/524*** | 51/538*** | 36/523*** | 41/559*** |
- In each cell, the proportion is shown as ″x/y″, with y for top-ranked genes and × for genes of interest. Enrichment p-value < 0.01 (*) or < 0.0001 (***) are marked.
- aTop-level is the fraction of the top-ranked genes/pairs in the total network nodes/edges. For differential expression genes (DEG), we used the node-wise fraction; for differential co-expression genes (DCGs) deriving from pairs, we used the edge-wise fraction. A same fraction of pairs involve a greater number of genes.
- bTransition names: Normal to Cirrhosis (N-C), Cirrhosis to Dysplasia (C-D), Dysplasia to Early HCC (D-E), and Early HCC to Advanced HCC (E-A).