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Table 2 Top 20 predicted drugs and corresponding BRC-MoA for similar effect prediction for E2.

From: BRCA-Monet: a breast cancer specific drug treatment mode-of-action network for treatment effective prediction using large scale microarray database

Rank Drug Mean Expression MoA
1 0198306-0000 2.060663 BRCA_MoA7
2 guaifenesin 0.136039 BRCA_MoA7
3 0317956-0000 0.127664 BRCA_MoA7
4 Estradiol 2.002982 BRCA_MoA64
5 norethisterone 1.514845 BRCA_MoA64
6 alpha-estradiol 1.459319 BRCA_MoA64
7 estropipate 1.288005 BRCA_MoA64
8 epitiostanol 1.009552 BRCA_MoA64
9 nefopam 0.84901 BRCA_MoA64
10 kaempferol 0.795197 BRCA_MoA64
11 noretynodrel 0.76267 BRCA_MoA64
12 levonorgestrel 0.71241 BRCA_MoA64
13 naringenin 0.554154 BRCA_MoA64
14 aminophylline 0.541906 BRCA_MoA64
15 etynodiol 0.389381 BRCA_MoA64
16 ethisterone 0.239267 BRCA_MoA64
17 epiandrosterone 0.207091 BRCA_MoA64
18 oxybenzone 0.176137 BRCA_MoA64
19 megestrol -0.40088 BRCA_MoA64
20 estrone -0.81855 BRCA_MoA64
  1. E2 is ranked 4th (highlighted).