Table 2 Top 20 predicted drugs and corresponding BRC-MoA for similar effect prediction for E2.

1

0198306-0000

2.060663

BRCA_MoA7

2

guaifenesin

0.136039

BRCA_MoA7

3

0317956-0000

0.127664

BRCA_MoA7

4

Estradiol

2.002982

BRCA_MoA64

5

norethisterone

1.514845

BRCA_MoA64

6

alpha-estradiol

1.459319

BRCA_MoA64

7

estropipate

1.288005

BRCA_MoA64

8

epitiostanol

1.009552

BRCA_MoA64

9

nefopam

0.84901

BRCA_MoA64

10

kaempferol

0.795197

BRCA_MoA64

11

noretynodrel

0.76267

BRCA_MoA64

12

levonorgestrel

0.71241

BRCA_MoA64

13

naringenin

0.554154

BRCA_MoA64

14

aminophylline

0.541906

BRCA_MoA64

15

etynodiol

0.389381

BRCA_MoA64

16

ethisterone

0.239267

BRCA_MoA64

17

epiandrosterone

0.207091

BRCA_MoA64

18

oxybenzone

0.176137

BRCA_MoA64

19

megestrol

-0.40088

BRCA_MoA64

20

estrone

-0.81855

BRCA_MoA64