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Table 4 Top 20 prediction result generated from cMap using GSE4025 E2 treatment signature as a query

From: BRCA-Monet: a breast cancer specific drug treatment mode-of-action network for treatment effective prediction using large scale microarray database

Rank Cmap name Mean N Enrichment P Specificity
1 MS-275 -0.954 2 -1.000 0.00000 0.0217
2 Vorinostat -0.697 12 -0.855 0.00000 0.0266
3 Trichostatin A -0.597 182 -0.735 0.00000 0.0000
4 Cephaeline -0.564 5 -0.889 0.00006 0.0361
5 Scriptaid -0.701 3 -0.962 0.00018 0.0000
6 Prochlorperazine -0.276 16 -0.506 0.00018 0.0472
7 Mefloquine -0.481 5 -0.805 0.00064 0.0278
8 5252917 0.657 2 0.977 0.00087 0.0000
9 Raloxifene -0.465 7 -0.670 0.00114 0.0130
10 perhexiline -0.476 4 -0.821 0.00193 0.0168
11 Ceforanide 0.199 4 0.813 0.00235 0.0207
12 Bacitracin 0.516 3 0.890 0.00252 0.0068
13 Ikarugamycin -0.525 3 -0.886 0.00292 0.0152
14 Iloprost 0.353 3 0.876 0.00354 0.0197
15 Isoxican 0.290 5 0.722 0.00375 0.0549
16 Diethylstilbestrol 0.413 6 0.666 0.00399 0.0737
17 Bufexamac -0.404 4 -0.786 0.00426 0.0000
18 Norcyclobenzaprine -0.404 4 -0.778 0.00501 0.0310
19 Riboflavin -0.412 4 -0.777 0.00511 0.0000
20 arachidonyltrifluoromethane 0.576 2 0.946 0.00535 0.0000