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Figure 1 | BMC Systems Biology

Figure 1

From: Gene and isoform expression signatures associated with tumor stage in kidney renal clear cell carcinoma

Figure 1

Correlation of gene and isoform profiles in terms of log 2 fold changes (FCs). (A) Correlation of genes and major isoforms. (B) Correlation of differentially expressed genes using the criteria of FC ≥ 2 and FDR ≤ 0.001 and their corresponding major isoforms. Red or green points depict both significant gene and major isoform up-regulation or down-regulation, respectively. Blue points denote only significant gene expression changes without major isoform expression changes. (C) Correlation of differentially expressed isoforms using the criteria of FC ≥ 2 and FDR ≤ 0.001 and their corresponding genes. Red or green points depict both significant gene and isoform up-regulation or down-regulation, respectively. Purple points denote only significant isoform expression changes without gene level changes. (D) Venn diagram showing the number of genes with significant overall mRNA expression changes and genes with significant isoform expression changes.

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