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Table 2 Pathway analysis for the eight alternative splicing isoforms.

From: Novel alternative splicing isoform biomarkers identification from high-throughput plasma proteomics profiling of breast cancer

PathwayID PathwayName Molecule
200017 p73 transcription factor network BRCA2;EP300
200141 FOXM1 transcription factor network EP300;BRCA2
200200 Validated targets of C-MYC transcriptional repression EP300;ERBB2
hsa04520 Adherens junction ERBB2;EP300
hsa05212 Pancreatic cancer ERBB2;BRCA2
1306955 GRB7 events in ERBB2 signaling ERBB2
1358803 Downregulation of ERRB2:ERBB3 signaling ERBB2
168253 Host Interactions with Influenza Factors PBRM1
168268 Virus Assembly and Release PBRM1
168270 Fusion and Uncoating of the Influenza Virion PBRM1
168275 Entry of Influenza Virion into Host Cell via Endocytosis PBRM1
168303 Packaging of Eight RNA Segments PBRM1
168330 Viral RNP Complexes in the Host Cell Nucleus PBRM1
192814 vRNA Synthesis PBRM1
192869 cRNA Synthesis PBRM1
200159 ErbB receptor signaling network ERBB2
168277 Influenza Virus Induced Apoptosis PBRM1
168288 Fusion of the Influenza Virion to the Host Cell Endosome PBRM1
168298 Release PBRM1
168302 Budding PBRM1
168336 Uncoating of the Influenza Virion PBRM1
192905 vRNP Assembly PBRM1
73951 Homologous recombination repair of replication-independent double-strand breaks BRCA2
918233 TRAF3-dependent IRF activation pathway EP300
73888 Homologous Recombination Repair BRCA2
76003 Presynaptic phase of homologous DNA pairing and strand exchange BRCA2
76010 Homologous DNA pairing and strand exchange BRCA2
h_hifPathway Hypoxia-Inducible Factor in the Cardiovascular System EP300
h_pitx2Pathway Multi-step Regulation of Transcription by Pitx2 EP300
h_ppargPathway Role of PPAR-gamma Coactivators in Obesity and Thermogenesis EP300
h_RELAPathway Acetylation and Deacetylation of RelA in The Nucleus EP300
hsa05200 Pathways in cancer ERBB2;BRCA2;EP300
h_carm1Pathway Transcription Regulation by Methyltransferase of CARM1 EP300
h_melanocytepathway Melanocyte Development and Pigmentation Pathway EP300
h_pelp1Pathway Pelp1 Modulation of Estrogen Receptor Activity EP300
h_vdrPathway Control of Gene Expression by Vitamin D Receptor EP300
hsa05215 Prostate cancer ERBB2;EP300
h_il7Pathway IL-7 Signal Transduction EP300
168325 Viral Messenger RNA Synthesis PBRM1
1963640 GRB2 events in ERBB2 signaling ERBB2
419524 Fanconi Anemia pathway BRCA2
73890 Double-Strand Break Repair BRCA2
416572 Sema4D induced cell migration and growth-cone collapse ERBB2
h_g2Pathway Cell Cycle: G2/M Checkpoint EP300
h_mef2dPathway Role of MEF2D in T-cell Apoptosis EP300
h_atrbrcaPathway Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility BRCA2
h_her2Pathway Role of ERBB2 in Signal Transduction and Oncology EP300
h_nthiPathway NFkB activation by Nontypeable Hemophilus influenzae EP300
h_p53hypoxiaPathway Hypoxia and p53 in the Cardiovascular system EP300
h_tgfbPathway TGF beta signaling pathway EP300
1250196 SHC1 events in ERBB2 signaling ERBB2
200025 Signaling events mediated by HDAC Class III EP300
hsa03440 Homologous recombination BRCA2
200164 Retinoic acid receptors-mediated signaling EP300
400685 Sema4D in semaphorin signaling ERBB2
933541 TRAF6 mediated IRF7 activation EP300