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Figure 3 | BMC Systems Biology

Figure 3

From: Identification of key regulators in glycogen utilization in E. coli based on the simulations from a hybrid functional Petri net model

Figure 3

Simulation results of HFPN model of extended center metabolism pathway in E. coli. Solid-curve is simulation result of this work. Red-bar denotes experimental data of our previous work [1]. From these results, (1) when glucose is present, PTS enzymes are in a non-phosphorylated state; and when there is no glucose, they are phosphorylated; (2) the first peak of glycolysis and PP pathway metabolites occur just after glycogen is consumed; (3) the second peak of these metabolites is due to the glucose uptake. The whole simulation results are in Figure S5 (see Additional file 5).

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