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Figure 4 | BMC Systems Biology

Figure 4

From: Identification of key regulators in glycogen utilization in E. coli based on the simulations from a hybrid functional Petri net model

Figure 4

Systematically understanding of the phases of extent center metabolism in an E. coli along its whole lifetime. A illustrates experiment and simulation behaviors of some major metabolites and enzymes, B shows sugar and phosphate flux processes of E. coli utilizing glucose and glycogen. Same color background areas of A and B are of the same phases. In B: Blue colored PTS represents unphosphorylated PTS, orange colored PTS is phosphorylated PTS. Blue filled arrows indicate carbon flux routes, in which deeper blue color represents more flowing amount; orange color filled arrows indicate phosphate flux routes, in which deeper orange color represents more flowing amount. Closed red locks means inactivated pathway; open green locks means activated pathway. The whole orange colored E. coli marked with "HPr" indicates HPr is scattered in cytosol; only orange colored pole E. coli marked with "HPr" indicates HPr is at poles.

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