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Table 1 Comparison of our results generated from the dataset of Harbison et al. to randomly assigned TF-gene pair lists for functional enrichment and prevalence of protein-protein interaction validation.

From: Inferring functional transcription factor-gene binding pairs by integrating transcription factor binding data with transcription factor knockout data

  Harbison et al.
  This study Random result One-tailed p -value
Functional enrichment 62/72 44.8 ± 3.53 2.76E-36 (t = -34.41)
Prevalence of PPI 53/72 17.68 ± 3.78 7.04E-50 (t = -66.13)