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Table 4 Functional enrichment analysis of H. sapiens proteins involved in the host-pathogen PPI dataset predicted by the stringent DDI-based approach.

From: Stringent DDI-based Prediction of H. sapiens-M. tuberculosis H37Rv Protein-Protein Interactions

GO terms

p-value

GO:0050660 FAD binding

2.27E-11

GO:0016462 pyrophosphatase activity

3.64E-06

GO:0004022 alcohol dehydrogenase (NAD) activity

8.70E-06

GO:0032559 adenyl ribonucleotide binding

9.27E-05

GO:0042626 ATPase activity, coupled to transmembrane movement of substances

6.54E-04

GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity

1.09E-03

GO:0042625 ATPase activity, coupled to transmembrane movement of ions

1.27E-03

GO:0000287 magnesium ion binding

8.04E-03

GO:0004466 long-chain-acyl-CoA dehydrogenase activity

1.28E-02

GO:0003960 NADPH:quinone reductase activity

2.55E-02

GO:0070402 NADPH binding

2.55E-02

GO:0004745 retinol dehydrogenase activity

6.25E-02

GO:0019841 retinol binding

7.45E-02

GO:0042288 MHC class I protein binding

9.81E-02

  1. This table summarizes the significantly enriched level 5 MF (Molecular Function) GO terms for H. sapiens proteins involved in the host-pathogen PPI dataset predicted by the stringent DDI-based approach. The analysis is produced using the DAVID database (threshold "count > 2, p-value < 0.1").