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Table 3 GO biological process term enrichment for TPPIN

From: Identification of core T cell network based on immunome interactome

GO ID Term Number of significant vs. annotated genes Expected number of genes Raw vs. adjusted P value
GO:0051251 positive regulation of lymphocyte activation 128/61 32.51 5.40 × 10-09/9.74 × 10-07
GO:0043067 regulation of programmed cell death 289/114 73.41 4.77 × 10-10/4.60 × 10-07
GO:0050776 regulation of immune response 313/118 79.51 6.79 × 10-09/1.11 × 10-06
GO:0048523 negative regulation of cellular process 401/142 101.86 1.05 × 10-08/1.62 × 10-06
GO:0050867 positive regulation of cell activation 144/64 36.58 7.04 × 10-08/5.59 × 10-06
GO:0048584 positive regulation of response to stimulus 401/140 101.86 5.10 × 10-08/4.40 × 10-06
GO:0042981 regulation of apoptotic process 285/113 72.39 4.04 × 10-10/4.60 × 10-07
GO:0007243 intracellular protein kinase cascade 330/121 83.82 3.13 × 10-08/3.40 × 10-06
GO:0019221 Cytokine mediated signaling pathway 163/73 41.40 3.85 × 10-09/8.07 × 10-07
GO:0006468 protein phosphorylation 313/116 79.51 3.63 × 10-08/3.51 × 10-06
  1. The “universe” is the immunome protein data and the enrichment is for the filtered immunome interactome, the T cell PPI network (TPPIN).