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Table 3 GO biological process term enrichment for TPPIN

From: Identification of core T cell network based on immunome interactome

GO ID

Term

Number of significant vs. annotated genes

Expected number of genes

Raw vs. adjusted P value

GO:0051251

positive regulation of lymphocyte activation

128/61

32.51

5.40 × 10-09/9.74 × 10-07

GO:0043067

regulation of programmed cell death

289/114

73.41

4.77 × 10-10/4.60 × 10-07

GO:0050776

regulation of immune response

313/118

79.51

6.79 × 10-09/1.11 × 10-06

GO:0048523

negative regulation of cellular process

401/142

101.86

1.05 × 10-08/1.62 × 10-06

GO:0050867

positive regulation of cell activation

144/64

36.58

7.04 × 10-08/5.59 × 10-06

GO:0048584

positive regulation of response to stimulus

401/140

101.86

5.10 × 10-08/4.40 × 10-06

GO:0042981

regulation of apoptotic process

285/113

72.39

4.04 × 10-10/4.60 × 10-07

GO:0007243

intracellular protein kinase cascade

330/121

83.82

3.13 × 10-08/3.40 × 10-06

GO:0019221

Cytokine mediated signaling pathway

163/73

41.40

3.85 × 10-09/8.07 × 10-07

GO:0006468

protein phosphorylation

313/116

79.51

3.63 × 10-08/3.51 × 10-06

  1. The “universe” is the immunome protein data and the enrichment is for the filtered immunome interactome, the T cell PPI network (TPPIN).