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Table 4 Essential genes overrepresentation

From: Identification of core T cell network based on immunome interactome

  Number of genes Number of genes annotated in MGI Number of lethality genes annotated in MGIa Expected number of lethality genes in MGI P-value for hypergeometric test
Immunome interactome 1140 949 312   
TPPIN 288 256 105 59 1.37 × 10-10
  1. The T cell PPI network is the resulting network after filtering the immunome interactome. MGIa is the Mouse Genome Informatics database.