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Figure 3 | BMC Systems Biology

Figure 3

From: Age-correlated stress resistance improves fitness of yeast: support from agent-based simulations

Figure 3

Numerical competition experiments. (A) Example of one simulation at intermediate heat shock severity and frequency (H a  = 0.7, F h  = 0.14 d-1). Cell density of 10 competitors. Abrupt drops in concentrations correspond to heat shocks. (B) Summary of tournament-style competitions. Optimal Tsl1/Tps3 expression parameters for a number of (B1) heat shock severities (H a varies, F h  = 0.14 d-1) and (B2) frequencies (H a  = 0.7, F h varies). Constant: e c,Tsl1 in μM, Age-dependent: e a,Tsl1 in μM, Stochastic: f r,Tsl1 / 10. Symbols are mean +/- one standard deviation of ten replicate experiments.

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