Evaluation of the lower protein limit in the budding yeast Saccharomyces cerevisiae using TIPI-gTOW

BMC Systems Biology

Table 2 Known genetic interactions with CDC20 mutation listed in the Saccharomyces Genome Database*

Gene	Genetic interaction with the cdc20 Mutant	Description	References
BUB2	Synthetic Rescue	Temperature sensitivity of cdc20-1(ts) is rescued by bub2 deletion.	[27]
CDH1	Synthetic Lethality	cdc20-1(ts) shows synthetic lethality with cdh1 deletion.	[28]
CIN8	Dosage Lethality	In the absence of CIN8, overexpression of CDC20 is lethal.	[29]
CLB2	Negative Genetic	Growth defect of cdc20_tsq368 increases with clb2 deletion.	[13]
LTE1	Synthetic Lethality	cdc20-1(ts) shows synthetic lethality with lte1 deletion.	[28]
MAD2	Phenotypic Suppression	cdc20 blocks the premature degradation of Pds1 observed in a mad2 mutant.	[30]
SIC1	Synthetic Lethality	cdc20-1(ts) shows synthetic lethality with sic1 deletion.	[28]

*When synonymous genetic interactions were reported in more than one study, one representative is listed.

ISSN: 1752-0509