Figure 4
From: Stress induced telomere shortening: longer life with less mutations?
Cell-to-cell variability is required for the beneficial effect of SITS. The colorcoded are the ratios between the average SITS and TS mutation rates, R M , (A) and longevities, R L (B). The ratios are shown as function of average level of DNA damage, <D> and cell-to-cell variability in DNA damage, σ D /<D>. The slice at σ D /<D>=1.5 would correspond to the ratios of the red and orange lines in Figure 3.