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Table 1 PubMed and PMC searches for OI-MET genes and cancer, BC, PC, and MET

From: A bioinformatics approach reveals novel interactions of the OVOL transcription factors in the regulation of epithelial – mesenchymal cell reprogramming and cancer progression

For 739 OI-MET genes, number found in: PubMed queries for % PubMed p-value PMC queries for % PMC p-value
(“cancer”[Text Word] + OR + “neoplasms”[Text Word]) 521 70.5% < 0.01 703 95.1% < 0.01
(“breast cancer”[Text Word] + OR + “breast neoplasms”[Text Word]) 344 46.5% < 0.01 699 94.6% < 0.01
(“prostate cancer”[Text Word] + OR + “prostate neoplasms”[ Text Word]) 228 30.9% < 0.01 679 91.9% < 0.01
(“epithelial- mesenchymal transition”[ MeSH Terms]) 91 12.3% < 0.0001 292 39.5% < 0.0001
For All 36, 973 HGNC Genes, Number found in: PubMed queries for    PMC queries for % PMC  
(“epithelial- mesenchymal transition”[ MeSH Terms]) 995 2.7%   1669 4.5%  
  1. “Cancer”, “breast cancer”, and “prostate cancer” text word searches show that a high proportion of OI-MET genes are associated with these concepts in the literature. “Epithelial-mesenchymal transition” MeSH term searches show a significant enrichment of this annotation in the OI-MET set, relative to all genes: 12.3% ÷ 2.7% = 4.6 Fold Enrichment for PubMed; 39.5% ÷ 4.5% = 8.8 Fold Enrichment for PMC; both with p-value < 0.0001.