Table 2 Regulation of AP1, STAT1, STAT3, and NFKB expression by OVOLS
BC fold change | PC fold change | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Gene | Expression level | OVOL1 | OVOL2 | OVOL1&2 | Up/Down switch | OVOL1 | OVOL2 | OVOL1&2 | Up/Down switch | |
AP1 | FOS (c- Fos) | Gene | 1.4 | 1.4 | 1.4 | 1.0 | 0.8 | 1.0 | ||
FOSB | Gene | 1.0 | 2.1 | 1.1 | Up | 0.7 | 0.5 | 0.4 | Down | |
NM _006732 | 2.6 | 0.0 | 0.0 | Switch | 10.0 | 10.0 | 10.0 | Switch | ||
NM _001114171 | 0.9 | 2.3 | 1.1 | 0.7 | 0.5 | 0.4 | ||||
FOSL1 (Fra- 1) | Gene | 0.9 | 0.9 | 0.8 | 1.1 | 1.0 | 0.7 | |||
FOSL2 (Fra- 2) | Gene | 0.7 | 0.7 | 0.6 | Down | 0.8 | 1.2 | 1.1 | ||
JUN (c- Jun) | Gene | 1.0 | 0.9 | 0.8 | 0.5 | 0.5 | 0.5 | Down | ||
JUNB | Gene | 1.5 | 2.2 | 2.1 | Up | 1.2 | 1.9 | 1.4 | Up | |
JUND | Gene | 1.1 | 1.1 | 1.3 | 1.2 | 1.6 | 1.2 | Up | ||
STAT | STAT1 | Gene | 1.1 | 1.3 | 1.0 | 1.0 | 1.4 | 2.0 | Up | |
NM _007315 | 1.1 | 1.3 | 1.0 | 1.1 | 1.4 | 1.9 | Up | |||
NM _139266 | 1.2 | 1.3 | 1.1 | 0.8 | 1.7 | 2.2 | Up | |||
STAT3 | Gene | 0.9 | 1.2 | 0.9 | 0.0 | 0.4 | 6.3 | Up/ down | ||
NM _139276 | 0.5 | 1.6 | 0.9 | Up/ down | 0.0 | 0.4 | 0.0 | Switch | ||
NM _003150 | 0.8 | 1.2 | 0.9 | 0.0 | 1.0 | 10.0 | ||||
NM _213662 | 1.0 | 1.2 | 0.9 | 0.1 | 1.2 | 8.6 | Up/ down | |||
NFKB | NFKB1 (NFkB1) | Gene | 1.0 | 1.3 | 1.2 | 1.0 | 1.1 | 1.0 | ||
NM _003998 | 1.0 | 1.3 | 1.2 | 1.3 | 1.1 | 1.2 | ||||
NM _001165412 | 1.0 | 1.2 | 1.2 | 0.8 | 1.0 | 0.9 | ||||
NFKB2 (NFkB2) | Gene | 0.9 | 1.5 | 1.2 | Up | 1.4 | 1.7 | 0.8 | Up /down | |
NM _001077494 | 0.9 | 1.5 | 1.0 | Up | 1.9 | 3.8 | 0.8 | Up | ||
NM _002502 | 0.7 | 1.6 | 0.9 | Up | 1.3 | 1.9 | 0.7 | Up | ||
NM _001261403 | 0.9 | 1.4 | 0.9 | 1.4 | 1.4 | 0.8 | ||||
REL (c- Rel) | Gene | 1.2 | 1.3 | 1.1 | 1.6 | 2.2 | 1.6 | Up | ||
RELA | Gene | 1.0 | 1.1 | 1.1 | 0.9 | 0.9 | 0.8 | |||
NM _021975 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | ||||
NM _001145138 | 1.0 | 1.1 | 1.1 | 0.9 | 0.9 | 0.8 | ||||
RELB | Gene | 0.8 | 1.5 | 1.1 | Up | 1.3 | 2.4 | 1.0 | Up | |