Figure 5
From: An integrative modeling framework reveals plasticity of TGF-β signaling
Plasticity of gene responses to combinations of TGF-β with other extracellular stimuli. 49 genes (red nodes) are regulated through signaling trajectories containing TGF-β (yellow node) and at least one other extracellular stimulus (blue nodes). The size of the nodes is relative to the number of edges. CCR5, GADD45A/B, MIP1A/B, GranzymeA/B, IL1RA and IL17F are the most represented genes and share the largest number of combinations in their trajectories.