Four-way Venn diagrams for four of the reconstructed metabolic models. Four-way Venn diagrams for the number of reactions (A) and genes (B) in i MR1_799 (blue), i MR4_812 (green), i W3181_789 (red), and i OS217_672 (orange) metabolic models. The number in parenthesis next to the model name outside of each rectangular box indicates the total number of reactions (panel A) or genes (panel B) in that model. Note that total number of reactions here excludes exchange reactions to better represent metabolic reactions in the models. The numbers within the boxes indicate the total number of reactions (panel A) or genes (panel B) that are shared among the overlapping models. The small colored squares above these numbers indicate the models that are overlapping.