Transcriptional override: a regulatory network model of indirect responses to modulations in microRNA expression

BMC Systems Biology

Table 1 MiRNA expression profiling identified 31 significantly differentially expressed miRNAs between OSE and CEPI

MicroRNA	P-value	Fold-change	MicroRNA	P-value	Fold-change
MIR7	0.00004	25.81	MIR106b	0.00204	32.90
MIR10a	0.00305	28.25	MIR128	0.00542	15.78
MIR17	0.01120	14.12	MIR130b	0.03129	11.71
MIR18a	0.00001	38.05	MIR141	0.00000	118.60
MIR18b	0.00000	46.21	MIR143	0.00792	5.98
MIR19a	0.00001	41.64	MIR148a	0.00406	10.70
MIR19b	0.00103	61.39	MIR148b	0.01725	7.94
MIR20a	0.00707	14.42	MIR155	0.00179	35.75
MIR20b	0.03363	19.16	MIR181d	0.02989	8.40
MIR21	0.01296	14.12	MIR182	0.00046	58.49
MIR25	0.01993	5.58	MIR200a	0.00264	39.12
MIR29b	0.00874	23.10	MIR200b	0.01871	14.52
MIR30b	0.01763	11.55	MIR200c	0.00232	13.36
MIR30c	0.01292	26.54	MIR205	0.00018	67.18
MIR93	0.02678	9.58	MIR429	0.00181	21.11
MIR106a	0.00505	20.53

Expression profiles for miRNAs in OSE and CEPI samples were determined using the miRChip system (Asuragen Inc.). Human probe sets with >65% present calls in either of the two groups (OSE and CEPI) were selected for analysis. All reported microarray data are described in accordance with MIAME guidelines. The processed and raw data files for the samples used in this study have been deposited in the Gene Expression Omnibus (GEO) as SuperSeries GSE42460.

ISSN: 1752-0509