Gene co-citation networks associated with worker sterility in honey bees

BMC Systems Biology

Table 2 Enrichment analysis of gene networks

Category	GO term	GO number	NG¹	Average O/E
Ovary Activation	Reproduction	GO:0000003	250	3.06
	Female gamete generation	GO:0007292	171	4.40
	Oogenesis	GO:0048477	171	4.46
Brain and Behaviour	Neuron differentiation	GO:0030182	208	6.35
	Response to chemical stimulus	GO:0042221	194	4.55
Signaling	Signal transduction	GO:0007165	253	3.17
	Cell communication	GO:0007154	332	3.05
Foraging/Flight Related	Compound eye development	GO:0048749	109	4.83
	Locomotion	GO:0040011	141	5.02

For each network that we inferred (Networks 1-3) we found the GO terms that are most likely to represent the network’s biological functions. Sixty biological processes were significantly enriched among all nine networks (P < 0.01). Nine selected processes, the number of genes associated with these processes, as well as the observed/expected ratios averaged over all networks, are presented.
¹The total number of genes found in all networks associated with the GO term.

ISSN: 1752-0509